MCQ of Pharmaceutical Biotechnology: for competative Exam

MCQ of Pharmaceutical Biotechnology: for competative Exam

1. Metabolic intermediates found in living system which are essential for

growth and life is called___________

A. Saponins

B. Tannins

C. Secondary metabolite

D. Primary metabolites

 

2. Which of the following is NOT the class of secondary metabolite.

A. Amino acids

B. Terpenes

C. Phenolics

D. Alkaloids

 

3. Name the class of secondary metabolites which is characterized by

the presence of the hydroxyl group with an aromatic ring?

A. Glycoside

B. Phenolics

C. Alkaloids

D. Terpenes

 

4. The production of secondary metabolites requires the use of _____.

A. Meristem

B. Protoplast

C. Axillary buds

D. Cell suspension

 

5. Which of the following does NOT take part in the biosynthesis of

terpenes?

A. Mevalonic acid

B. Methylerythritol phosphate

C. Acetyl-COA

D. Phenol

 

6. Beta-carotene, a plant pigment falls under which of the following

classes of terpenes?

A. Triterpenes

B. Teteraterpenes

C. Diterpenes

D. Polyterpenes

 

7. In Penicillium chrysogenum, the maximum antibiotic production

occurs during the __________.

A. The second phase

B. The third phase

C. First phase

D. In all three phases

 

8. What is meant by a reaction going in 94% enantiomeric excess?

A. The product contains 94% of one enantiomer and 6%

of the other enantiomer

B.The product contains an enantiomer which is 94%

pure.

C. The product contains 94% of one enantiomer and 6%

of other products

D. The product contains 97% of one enantiomer and 3%

of the other enantiomer

 

9. Which of the following species is used for producing

erythromycin?

A. S. erythreus

B. S. griseus

C. S. aureofaciens

D. S. griseoflavus

 

10. Antibacterial-resistant strains and species, sometimes referred

to as

A. "superbugs"

B. "superspecies"

C. "superbacteria"

D. "superaweed”

 

11. Drugs was not isolated from a natural source is…

A. Isoniazid

B. Artemisinin

C. Quinine

D. Morphine

 

12. What are adverse drug reactions (ADRs)?

A. The synergistic effects that are seen when some drugsare administered concurrently.

B. Responses to increased drug doses required to

achieve the same physiological outcome.

C. Unintended alternative physiological responses caused

by the drug that cause harm to the patient.

D. Harmful chemical interactions between two drugs that

are used to treat the same clinical symptoms.

 

13. What is meant by antibiotic resistance?

A.  It means our body has become resistant to the

antibiotic

B. It means the bacteria have developed antibiotic

resistance

C. Both (a) and (b)

D. None of the above

 

14. Which of the following is the most accurate method for microbial

assay of antibiotics?

A. Physical assay

B. Chemical assay

C. Biological assay

D. Chemical and biological assay

 

15. Which of the following strain used for production of Nystatin

A. Streptomyces noursei

B. Streptomyces aureofaciens

C. Streptomyces kanamyceticus

D. Streptomyces fradiae

 

16 . Which of the following has its antiviral action attributed to the

interference of protein synthesis?

A. Amantadine

B. Interferons

C. Acycloguanosine

D. 5’-iododeoxyuridine

 

17. Which of the following fermentation processes is used in the

production of penicillin?

A.  Aerobic fermentation followed by anaerobic

fermentation

B. Anaerobic fermentation

C. Aerobic fermentation

D. Anaerobic fermentation followed by aerobic

Fermentation

 

18. Which of the following statements is true according to

Amantadine

A. is a low-molecular weight compound

B. very effective against influenza A virus

C. influenza A infection is greatly reduced

D. All of the above

 

19. What is the clinical application of monoclonal antibodies?

A. Biosensors

B. Transplant rejection

C. Infectious disease

D. Purification of drugs

 

20. MAbs was modified for delivery of a toxin, radioisotope and

__________

A. Enzymes

B. Hormones

C. Drugs

D. Cytokine

 

21. Bispecific antibodies can bind with their Fab regions both to target

antigen and to _____________

A. Other antibodies

B. An effector cell

C. Proteins around

D. Prostaglandins

 

22. Why human cells are more preferred for the production of the

recombinant protein?

A. Say in culturing

B. More sterility

C. Can be easily harvested

D. Post-translational modification

 

23. What had helped the study of the structure of antibodies in 1970?

A. APC

B. Red blood cells

C. Killer cells

D. Cancer myeloma B-cell

 

24. Who invented the process of producing monoclonal antibodies in

1975?

A. Albert Einstein

B. Watson and Creek

C. Georges Köhler and César Milstein

D. Robert Hook

 

25. What do you add to Myeloma cells to receive HGPRT- myeloma

cells?

A. 8 – Azaguanine

B. Azaguanine

C. Nitrogen flush

D. Carbon dioxide flush