Hello friends, In today's article we see the MCQ's of Vitamins in biochemistry. So let's begin MCQ's of vitamin in biochemistry.
Vitamins MCQ’s in Biochemistry
1. Vitamins
are
(A) Accessory food factors
(B) Generally
synthesized in the body
(C) Produced in
endocrine glands
(D) Proteins in
nature
2. Vitamin
A or retinal is a
(A) Steroid
(B) Polyisoprenoid compound containing a cyclohexenyl
ring
(C)
Benzoquinone derivative
(D) 6-Hydroxychromane
3. β-Carotene,
precursor of vitamin A, is oxidatively
cleaved by
(A) β-Carotene dioxygenase
(B) Oxygenase
(C) Hydroxylase
(D) Transferase
4. Retinal
is reduced to retinol in intestinal mucosa by a specific retinaldehyde
reductase utilising
(A) NADPH + H+
(B) FAD
(C) NAD
(D) NADH + H+
5. Preformed Vitamin A is supplied by
(A) Milk, fat and liver
(B) All yellow vegetables
(C) All yellow
fruits
(D) Leafy green
vegetables
6. Retinol
and retinal are interconverted requiring dehydrogenase or reductase in
the presence of
(A) NAD or NADP
(B) NADH + H+
(C) NADPH
(D) FAD
7. Fat
soluble vitamins are
(A) Soluble
in alcohol
(B) one or
more Propene units
(C) Stored
in liver
(D) All these
8. The
international unit of vitamin A is
equivalent to the activity caused by
(A) 0.3 µg of Vitamin A alcohol
(B) 0.344
µg of Vitamin A alcohol
(C) 0.6 µg
of Vitamin A alcohol
(D) 1.0 µg
of Vitamin A alcohol
9. Lumirhodopsin
is stable only at temperature below
(A) -10°C
(B) -20°C
(C) -40°C
(D) -50°C
10. Retinol
is transported in blood bound to
(A) Aporetinol binding protein
(B) α2-Globulin
(C) β-Globulin
(D) Albumin
11. The
normal serum concentration of vitamin A in mg/100 ml is
(A) 5-10
(B) 15-60
(C) 100-150
(D) 0-5
12. One
manifestation of vitamin A deficiency
is
(A) Painful
joints
(B) Night blindness
(C) Loss of
hair
(D) Thickening
of long bones
13. Deficiency
of Vitamin A causes
(A) Xeropthalmia
(B)
Hypoprothrombinemia
(C)
Megaloblastic anemia
(D) Pernicious
anemia
14. An
important function of vitamin A is
(A) To act as
coenzyme for a few enzymes
(B) To play an integral role in protein
synthesis
(C) To prevent
hemorrhages
(D) To maintain the integrity of epithelial
tissue
15. Retinal
is a component of
(A) Iodopsin
(B) Rhodopsin
(C) Cardiolipin
(D)
Glycoproteins
16. Retinoic
acid participates in the synthesis
of
(A) Iodopsin
(B) Rhodopsin
(C) Glycoprotein
(D) Cardiolipin
17. On
exposure to light rhodopsin forms
(A) All trans-retinal
(B) Cis-retinal
(C) Retinol
(D) Retinoic
acid
18. Carr-Price
reaction is used to detect
(A) Vitamin A
(B) Vitamin D
(C) Ascorbic
acid
(D) Vitamin E
19. The
structure shown below is of
(A) Cholecalciferol
(B) 25-Hydroxycholecalciferol
(C)
Ergocalciferol
(D) 7-Dehydrocholesterol
Read more MCQ's of Hormones
20. Vitamin
D absorption is increased in
(A) Acid pH of
intestine
(B) Alkaline pH of intestine
(C) Impaired
fat absorption
(D) Contents
of diet
21. The
most potent Vitamin D metabolite is
(A) 25-Hydroxycholecalciferol
(B)
1,25-Dihydroxycholecalciferol
(C) 24,
25-Dihydroxycholecalciferol
(D) 7-Dehydrocholesterol
22. The
normal serum concentration of
25-hydroxycholecalciferol in ng/ml is
(A) 0-8
(B) 60-100
(C) 100-150
(D) 8-55
23. The
normal serum concentration of 1,25-dihydroxycholecalciferol in pg/ml is
(A) 26-65
(B) 1-5
(C) 5-20
(D) 80-100
24. The
normal serum concentration of 24,25-dihydroxycholecalciferol in ng/ml is
(A) 8-20
(B) 25-50
(C) 1-5
(D) 60-100
25. A poor
source of Vitamin D is
(A) Egg
(B) Butter
(C) Milk
(D) Liver
26. Richest
source of Vitamin D is
(A) Fish liver oils
(B) Margarine
(C) Egg
yolk
(D) Butter
27. Deficiency
of vitamin D causes
(A) Ricket and
osteomalacia
(B) Tuberculosis of bone
(C) Hypthyroidism
(D) Skin
cancer
28. One
international unit (I.U) of vitamin D
is defined as the biological activity of
(A) 0.025 µg of
cholecalciferol
(B) 0.025 µg of 7-dehydrocholecalciferol
(C) 0.025
µg of ergosterol
(D) 0.025
µg of ergocalciferol
29. The
β-ring of 7-dehydrocholesterol is cleaved to form cholecalciferol by
(A) Infrared
light
(B) Dim light
(C) Ultraviolet irridation with sunlight
(D) Light of
the tube lights
30. Calcitriol
synthesis involves
(A) Both liver and kidney
(B) Intestine
(C) Adipose
tissue
(D) Muscle
31. Insignificant
amount of Vitamin E is
present in
(A) Wheat germ
oil
(B) Sunflower
seed oil
(C) Safflower
seed oil
(D) Fish liver oil
32. The
activity of tocopherols is destroyed
by
(A) Commercial cooking
(B) Reduction
(C) Conjugation
(D) All of
these
33. The
requirement of vitamin E is increased
with greater intake of
(A)
Carbohydrates
(B) Proteins
(C) Polyunsaturated fat
(D) Saturated
fat
34. Vitamin
E reduces the requirement of
(A) Iron
(B) Zinc
(C) Selenium
(D) Magnesium
35. The
most important natural antioxidant
is
(A) Vitamin D
(B) Vitamin E
(C) Vitamin B12
(D) Vitamin K
36. Tocopherols
prevent the oxidation of
(A) Vitamin A
(B) Vitamin D
(C) Vitamin K
(D) Vitamin C
37. Creatinuria
is caused due to the deficiency
of vitamin
(A) A
(B) K
(C) E
(D) D
38. All the
following conditions produce a real or functional deficiency of vitamin K
except
(A) Prolonged
oral, broad spectrum antibiotic therapy
(B) Total lack of red meat in the diet
(C) The total
lack of green leafy vegetables in
the diet
(D) Being a new
born infant
39. Vitamin
K is found in
(A) Green leafy plants
(B) Meat
(C) Fish
(D) Milk
40. Function
of Vitamin A:
(A) Healing
epithelial tissues
(B) Protein synthesis regulation
(C) Cell growth
(D) All of these
41. Vitamin
K2 was originally isolated from
(A) Soyabean
(B) Wheat gram
(C) Alfa Alfa
(D) Putrid fish meal
42. Vitamin
synthesized by bacterial in the intestine is
(A) A
(B) C
(C) D
(D) K
43. Vitamin
K is involved in posttranslational modification of the blood clotting factors
by acting as cofactor for the enzyme:
(A) Carboxylase
(B)
Decarboxylase
(C) Hydroxylase
(D) Oxidase
44. Vitamin
K is a cofactor for
(A) Gamma carboxylation of glutamic acid residue
(B) β-Oxidation
of fatty acid
(C) Formation
of γ-amino butyrate
(D) Synthesis
of tryptophan
45. Hypervitaminosis
K in neonates may cause
(A) Porphyria
(B) Jaundice
(C) Pellagra
(D) Prolonged
bleeding
46. Dicoumarol
is antagonist to
(A) Riboflavin
(B) Retinol
(C) Menadione
(D) Tocopherol
47. In the
individuals who are given liberal quantities of vitamin C, the serum ascorbic
acid level is
(A) 1-1.4 µg/100 ml
(B) 2-4
µg/100 ml
(C) 1-10
µg/100 ml
(D) 10-20
µg/100 ml
48. The
vitamin which would most likely become deficient in an individual who
develop a completely carnivorous life style is
(A) Thiamin
(B) Niacin
(C) Vitamin C
(D) Cobalamin
49. In
human body highest concentration of ascorbic acid is found in
(A) Liver
(B) Adrenal cortex
(C) Adrenal
medulla
(D) Spleen
50. The
vitamin required for the formation of hydroxyproline (in collagen) is
(A) Vitamin C
(B) Vitamin A
(C) Vitamin D
(D) Vitamin E
51. Vitamin
required for the conversion of p-hydroxyphenylpyruvate to
homo-
gentisate is
(A) Folacin
(B) Cobalamin
(C) Ascorbic
acid
(D) Niacin
52. Vitamin
required in conversion of folic
acid to folinic acid is
(A) Biotin
(B) Cobalamin
(C) Ascorbic acid
(D) Niacin
53. Ascorbic
acid can reduce
(A) 2,
6-Dibromobenzene
(B) 2,
6-Diiodoxypyridine
(C) 2, 6-Dichlorophenol indophenol
(D) 2,
4-Dinitrobenzene
54. Sterilised
milk lacks in
(A) Vitamin A
(B) Vitamin D
(C) Vitamin C
(D) Thiamin
55. Scurvy
is caused due to the deficiency of
(A) Vitamin A
(B) Vitamin D
(C) Vitamin K
(D) Vitamin C
56. Both
Wernicke’s disease and beriberi can be reversed by administrating
(A) Retinol
(B) Thiamin
(C) Pyridoxine
(D) Vitamin B12
57. The
Vitamin B1 deficiency causes
(A) Ricket
(B) Nyctalopia
(C) Beriberi
(D) Pellagra
58. Concentration
of pyruvic acid and lactic acid in blood is increased due to deficiency
of the vitamin
(A) Thiamin
(B) Riboflavin
(C) Niacin
(D) Pantothenic
acid
59. Vitamin
B1 coenzyme (TPP) is involved in
(A) Oxidative decarboxylation
(B)
Hydroxylation
(C)
Transamination
(D)
Carboxylation
60. Increased
glucose consumption increases
the dietary requirement for
(A) Pyridoxine
(B) Niacin
(C) Biotin
(D) Thiamin
61. Thiamin
is oxidized to thiochrome in alkaline solution by
(A) Potassium
permanganate
(B) Potassium ferricyanide
(C) Potassium
chlorate
(D) Potassium
dichromate
62. Riboflavin
is a coenzyme in the reaction catalysed by the enzyme
(A) Acyl CoA
synthetase
(B) Acyl CoA dehydrogenase
(C) β-Hydroxy
acyl CoA
(D) Enoyl CoA
dehydrogenase
63. The
daily requirement of riboflavin for
adult in mg is
(A) 0-1.0
(B) 1.2-1.7
(C) 2.0-3.5
(D) 4.0-8.0
64. In new
born infants phototherapy may cause hyperbilirubinemia with deficiency
of
(A) Thiamin
(B) Riboflavin
(C) Ascorbic
acid
(D) Pantothenic
acid
65. Riboflavin
deficiency causes
(A) Cheilosis
(B) Loss of
weight
(C) Mental
deterioration
(D) Dermatitis
66. Magenta
tongue is found in the deficiency of the vitamin
(A) Riboflavin
(B) Thiamin
(C) Nicotinic
acid
(D) Pyridoxine
67. Corneal
vascularisation is found in deficiency of the vitamin:
(A) B1
(B) B2
(C) B3
(D) B6
68. The
pellagra preventive factor is
(A) Riboflavin
(B) Pantothenic
acid
(C) Niacin
(D) Pyridoxine
69. Pellagra
is caused due to the deficiency
of
(A) Ascorbic
acid
(B) Pantothenic
acid
(C) Pyridoxine
(D) Niacin
70. Niacin
or nicotinic acid is a monocarboxylic acid derivative of
(A) Pyridine
(B) Pyrimidine
(C) Flavin
(D) Adenine
71. Niacin
is synthesized in the body from
(A) Tryptophan
(B) Tyrosine
(C) Glutamate
(D) Aspartate
72. The
proteins present in maize are deficient
in
(A) Lysine
(B) Threonine
(C) Tryptophan
(D) Tyrosine
73. Niacin
is present in maize in the form of
(A) Niatin
(B) Nicotin
(C) Niacytin
(D) Nicyn
74. In the
body 1 mg of niacin can be
produced from
(A) 60 mg
of pyridoxine
(B) 60 mg of tryptophan
(C) 30 mg
of tryptophan
(D) 30 mg
of pantothenic acid
75. Pellagra
occurs in population dependent
on
(A) Wheat
(B) Rice
(C) Maize
(D) Milk
76. The
enzymes with which nicotinamide act
as coenzyme are
(A) Dehydrogenases
(B)
Transaminases
(C)
Decarboxylases
(D)
Carboxylases
77. Dietary
requirement of Vitamin D:
(A) 400 I.U.
(B) 1000
I.U.
(C) 6000
I.U.
(D) 700
I.U.
78. The
Vitamin which does not contain a ring
in the structure is
(A) Pantothenic acid
(B) Vitamin D
(C) Riboflavin
(D) Thiamin
79. Pantothenic
acid is a constituent of the
coenzyme involved in
(A)
Decarboxylation
(B)
Dehydrogenation
(C) Acetylation
(D) Oxidation
80. The
precursor of CoA is
(A) Riboflavin
(B)
Pyridoxamine
(C) Thiamin
(D) Pantothenate
81. ‘Burning
foot syndrome’ has been ascribed to the deficiency of
(A) Pantothenic acid
(B) Thiamin
(C) Cobalamin
(D) Pyridoxine
82. Pyridoxal
phosphate is central to
(A) Deamination
(B) Amidation
(C)
Carboxylation
(D) Transamination
83. The
vitamin required as coenzyme for the
action of transaminases is
(A) Niacin
(B) Pantothenic
acid
(C) Pyridoxal phosphate
(D) Riboflavin
84. Vitamin
B6 deficiency may occur during
therapy with
(A) Isoniazid
(B) Terramycin
(C) Sulpha
drugs
(D) Aspirin
85. Deficiency
of vitamin B6 may occur in
(A) Obese
person
(B) Thin person
(C) Alcoholics
(D) Diabetics
86. ‘Xanthurenic
acid index’ is a reliable criterion for the deficiency of the vitamin
(A) Pyridoxal
(B) Thiamin
(C) Pantothenic
acid
(D) Cobalamin
87. Epileptiform
convulsion in human infants have been attributed to the deficiency of
the vitamin
(A) B1
(B) B2
(C) B6
(D) B12
88. Biotin
is a coenzyme of the enzyme
(A) Carboxylase
(B) Hydroxylase
(C)
Decarboxylase
(D) Deaminase
89. The
coenzyme required for conversion of pyruvate to oxaloacetate is
(A) FAD
(B) NAD
(C) TPP
(D) Biotin
90. In
biotin-containing enzymes, the biotin is bound to the enzyme by
(A) An amide
linkage to carboxyl group of glutamine
(B) A covalent
bond with CO2
(C) An amide linkage to an amino group of lysine
(D) An amide
linkage to α-carboxyl group of
protein
91. A
molecule of CO2 is captured by biotin when it acts as coenzyme for
carboxyla-
tion reaction. The carboxyl group is co-valently
attached to
(A) A nitrogen (N1) of the biotin
molecule
(B) Sulphur of
thiophene ring
(C) α-Amino
group of lysine
(D) α-Amino
group of protein
92. Consumption
of raw eggs can cause
deficiency of
(A) Biotin
(B) Pantothenic
acid
(C) Riboflavin
(D) Thiamin
93. The
cofactor or its derivative required for the conversion of acetyl CoA to malonyl-
CoA is
(A) FAD
(B) ACP
(C) NAD+
(D) Biotin
94. A
cofactor required in oxidative decarboxylation of pyruvate is
(A) Lipoate
(B) Pantothenic
acid
(C) Biotin
(D) Para
aminobenzoic acid
95. The
central structure of B12 referred to as
corrin ring system consists of
(A) Cobalt
(B) Manganese
(C) Magnesium
(D) Iron
96. The
central heavy metal cobalt of vitamin B12 is coordinately bound to
(A) Cyanide group
(B) Amino group
(C) Carboxyl
group
(D) Sulphide
group
97. Vitamin
B12 has a complex ring structure (corrin ring) consisting of four
(A) Purine
rings
(B) Pyrimidine
rings
(C) Pyrrole rings
(D) Pteridine
rings
98. Emperical
formula of cobalamin is
(A) C63H88N12O14P.CO
(B) C61H82N12O12P.CO
(C) C61H88N12O14P.CO
(D) C63H88N14O14P.CO
99. A
deficiency of vitamin B12 causes
(A) Beri-Beri
(B) Scurvy
(C) Perniciuos anemia
(D) Ricket
100. Vitamin
B12 deficiency can be diagnosed by urinary excretion of
(A) Pyruvate
(B) Methylmalonate
(C) Malate
(D) Lactate
101. Subacute
combined degeneration of cord
is caused due to deficiency of
(A) Niacin
(B) Cobalamin
(C) Biotin
(D) Thiamin
102. Vitamin
required for metabolism of diols e.g. conversion of ethylene glycol to
acetaldehyde is
(A) Thiamin
(B) Cobalamin
(C) Pyridoxine
(D) Folic acid
103. Both
folic acid and methyl cobalamin (vitamin B12) are required in
(A) Deamination
of serine
(B) Deamination of threonine
(C) Conversion
of pyridoxal phosphate to pyridoxamine phosphate
(D) Methylation of homocystein to methionine
104. Folic
acid or folate consists of the
(A) Base pteridine,
p-amino benzoic acid and asparate
(B) Base
purine, p-amino benzoic acid and glutamate
(C) Base pteridine, p-amino benzoic acid and
glutamate
(D) Base
purine, p-hydroxy benzoic acid and glutamate
105. Folate
as a coenzyme is involved in the transfer and utilization of
(A) Amino group
(B) Hydroxyl
group
(C) Single carbon moiety
(D) Amido group
106. Folic
acid deficiency can be diagnosed by
increased urinary excretion of
(A)
Methylmalonate
(B) Figlu
(C)
Cystathionine
(D) Creatinine
107. Sulpha
drugs interfere with bacterial synthesis of
(A) Lipoate
(B) Vitamin E
(C) Tetrahydrofolate
(D) Ascorbic
acid
108. Folate
deficiency causes
(A) Microcytic
anemia
(B) Hemolytic
anemia
(C) Iron
deficiency anemia
(D) Megaloblastic anemia
109. Thiamin
is heat stable in
(A) Acidic medium
(B) Alkaline
medium
(C) Both (A)
and (B)
(D) None of
these
110. Thiamin
deficiency includes
(A) Mental
depression
(B) Fatigue
(C) Beriberi
(D) All of these
111. Thiamin
diphosphate is required for oxidative decarboxylation of
(A) α-Keto acids
(B) α-Amino
acids
(C) Fatty acids
(D) All of
these
112. Loss of
thiamin can be decreased by using
(A) Unpolished
rice
(B) Parboiled rice
(C) Whole wheat
flour
(D) All of these
113 . Daily
requirement of thiamin is
(A) 0.1 mg/1,000 Calories
(B) 0.5
mg/1,000 Calories
(C) 0.8
mg/1,000 Calories
(D) 1.0
mg/1,000 Calories
114. Thiamin
requirement is greater in
(A)
Non-vegetarians
(B) Alcoholics
(C) Pregnant
women
(D) Both B and C
115. People
consuming polished rice as their staple food are prone to
(A) Beriberi
(B) Pellagra
(C) Both (A)
and (B)
(D) None of
these
116. Riboflavin
is heat stable in
(A) Acidic
medium
(B) Alkaline
medium
(C) Neutral
medium
(D) Both (A) and (C)
117. FAD is a
coenzyme for
(A) Succinate
dehydrogenase
(B)
Glycerol-3-phosphate dehydrogenase
(C) Sphingosine
reductase
(D) All of these
118. Riboflavin
deficiency can cause
(A) Peripheral
neuritis
(B) Diarrhoea
(C) Angular stomatitis
(D) None of
these
119. Pellagra
preventing factor is
(A) Thiamin
(B) Riboflavin
(C) Niacin
(D) Pyridoxine
120. Niacin
contains a
(A) Sulphydryl
group
(B) Carboxyl group
(C) Amide group
(D) All of
these
121. NADP is
required as a coenzyme in
(A) Glycolysis
(B) Citric acid
cycle
(C) HMP shunt
(D)
Gluconeogenesis
122. NAD is
required as a coenzyme for
(A) Malate dehydrogenase
(B) Succinate dehydrogenase
(C)
Glucose-6-phosphate dehydrogenase
(D) HMG CoA
reductae
123. NAD is
required as a conenzyme in
(A) Citric acid
cycle
(B) HMP shunt
(C) β-Oxidation
of fatty acids
(D) Both (A) and (C)
124. Niacin
can be synthesised in human
beings from
(A) Histidine
(B)
Phenylalanine
(C) Tyrosine
(D) Tryptophan
125. Daily
requirement of niacin is
(A) 5 mg
(B) 10 mg
(C) 20 mg
(D) 30 mg
126. Niacin
deficiency is common in people
whose staple food is
(A) Wheat
(B) Polished
rice
(C) Maize and /or sorghum
(D) None of
these
127. In
pellagra, dermatitis usually affects
(A) Exposed parts of body
(B) Covered
parts of body
(C) Trunk only
(D) All parts
of the body
128. Niacin
deficiency can occur in
(A) Hartnup disease
(B)
Phenylketonuria
(C)
Alkaptonuria
(D) None of
these
129. Pantothenic
acid contains an amino acid
which is
(A) Aspartic
acid
(B) Glutamic
acid
(C) β-Alanine
(D)
β-Aminoisobutyric acid
130. Sulphydryl
group of coenzyme a is contri-
buted by
(A) β-Alanine
(B)
β-Aminoisobutyric acid
(C) Methionine
(D) Thioethanolamine
131. Coenzyme
A contains a nitrogenous base
which is
(A) Adenine
(B) Guanine
(C) Choline
(D)
Ethanolamine
132. The
following is required for the formation
of coenyzme A:
(A) ATP
(B) GTP
(C) CTP
(D) None of
these
133. Coenzyme
A is required for catabolism of
(A) Leucine
(B) Isoleucine
(C) Valine
(D) All of these
134. Deficiency
of pantothenic acid in human
beings can affect
(A) Nervous
system
(B) Digestive
system
(C) Both (A) and (B)
(D) None of
these
135. Pyridoxal
phosphate is a coenzyme for
(A) Glutamate
oxaloacetate transaminase
(B) Glutamate
pyruvate transaminase
(C) Tyrosine
transaminase
(D) All of these
136. Pyridoxal
phosphate is required as a
coenzyme in
(A)
Transamination
(B)
Transulphuration
(C)
Desulphydration
(D) All of these
137. Pyridoxal
phosphate is a coenzyme for
(A) Glycogen
synthetase
(B) Phosphorylase
(C) Both (A)
and (B)
(D) None of
these
138. Pyridoxine
deficiency can be diagnosed
by measuring urinary excretion of
(A) Pyruvic
acid
(B) Oxaloacetic
acid
(C) Xanthurenic acid
(D) None of
these
139. Pyridoxine
deficiency can be diagnosed by measuring the urinary excretion of
xanthurenic acid following a test dose of
(A) Glycine
(B) Histidine
(C) Tryptophan
(D) Pyridoxine
140. Pyridoxine
requirement depends upon the intake of
(A) Carbohydrates
(B) Proteins
(C) Fats
(D) None of
these
141. Anti-egg
white injury factor is
(A) Pyridoxine
(B) Biton
(C) Thiamin
(D) Liponic
acid
142. When
eggs are cooked
(A) Biotin is
destroyed but avidin remains unaffected
(B) Avidin is inactivated but biotin remains unaffected
(C) Both avidin
and biotin are inactivated
(D) Both avidin
and biotin remain unaffected
143. Biotin
is required as a coenzyme by
(A) Anaerobic
dehydrogenases
(B)
Decarboxylases
(C) Aerobic
dehydrogenases
(D) Carboxylases
144. Biotin
is a coenzyme for
(A) Pyruvate
carboxylase
(B) Acetyl CoA
carboxylase
(C) Propionyl
CoA carboxylase
(D) All of these
145. Lipoic
acid is a conenzyme for
(A) Pyruvate
dehydrogenase
(B) α-Ketoglutarate dehydrogenae
(C) Both (A) and (B)
(D) None of
these
146. Chemically,
lipoic acid is
(A) Saturated
fatty acid
(B) Unsaturated fatty acid
(C) Amino acid
(D) Sulphur containing fatty acid
147. Folic
acid contains
(A) Pteridine
(B) p-Amino
benzoic acid
(C) Glutamic
acid
(D) All of these
148. Conversion
of folate into tetrahydrofolate
requires
(A) NADH
(B) NADPH
(C) FMNH2
(D) FADH2
149. Riboflavin
deficiency symptoms are
(A) Glossitis
(B) stomatis
(C) Vomitting
(D) Both (A) and (B)
150. Vitamin
B12 forms coenzymes known as
(A) Cobamide
(B)
Transcobalamin I
(C)
Transcobalamin II
(D) Both (B)
and (C)
151. Methylcobalamin
is required for forma-
tion of
(A) Serin from
glycine
(B) Glycine from serine
(C) Methionine from homocysteine
(D) All of
these
152. Absorption
of Vitamin B12 requires the
presence of
(A) Pepsin
(B)
Hydrochloric acid
(C) Intrinsic
factor
(D) Boh (B) and (C)
153. Intrinsic
factor is chemically a
(A) Protein
(B) Glycoprotein
(C)
Mucopolysaccaride
(D) Peptide
154. Chemically,
Extrinsic Factor of Castle is a
(A) Mucoprotein
(B) Glycoprotein
(C)
Mucopolysaccharide
(D) Cyanocobalaminm
155. Vitamin
B12 is
(A) Not stored
in the body
(B) Stored in
bone marrow
(C) Stored in liver
(D) Stored in
RE cells
156. Vitamin
B12 is transported in blood by
(A) Albumin
(B) Transcortin
(C)
Transcobalamin I
(D) Transcobalamin II
157. Vitamin
B12 is synthesized by
(A) Bacteria only
(B) Plants only
(C) Animals
only
(D) Both (A)
and (C)
158. Deficiency
of vitamin B12 can occur because
of
(A) Decreased
intake of vitamin B12
(B) Atrophy of
gastric mucosa
(C) Intestinal
malabsorption
(D) All of these
159. Deficiency
of vitamin B12 can be diagonised
by
(A) Carr-Price
reaction
(B) Ames assay
(C)
Watson-Schwartz test
(D) Schilling test
160. Gastyrectomy
leads to megaloblastic
anaemia within a few
(A) Days
(B) Weeks
(C) Months
(D) Years
161. Ascorbic
acid is required to synthesise all
of the following except
(A) Collagen
(B) Bile acids
(C) Bile pigments
(D) Epinephrine
162. Vitamin
C enhances the intestinal
absorption of
(A) Potassium
(B) Iodine
(C) Iron
(D) None of
these
163. Vitamin
C activity is present in
(A) D-Ascorbic
acid
(B)
D-Dehydroascorbic acid
(C) L-Ascorbic acid
(D) Both A and
B
164. Vitamin
C is required for the synthesis of
(A) Bile acids from cholesterol
(B) Bile salts from bile acids
(C) Vitamin D
from cholesterol
(D) All of
these
165. Deficiency
of vitamin C causes
(A) Beriberi
(B) Pellagra
(C) Pernicious
anaemia
(D) Scurvy
166. An early
diagnosis of vitamin C deficiency
can be made by
(A) Measuring
plasma ascorbic acid
(B) Measuring
urinary ascorbic acid
(C) Ascorbic acid saturation test
(D) All of
these
167. Daily
requirement of vitamin C in adults
is about
(A) 100 mg
(B) 25 mg
(C) 70 mg
(D) 100 mg
168. The
vitamin having the highest daily requirement among the following is
(A) Thiamin
(B) Ribovflavin
(C) Pyridoxine
(D) Ascorbic acid
169. Anaemia
can occur due to the deficiency
of all the following except
(A) Thiamin
(B) Pyridoxine
(C) Folic acid
(D)
Cyanocobalamin
170. A
vitamin which can be synthesized by
human beings is
(A) Thiamin
(B) Niacin
(C) Folic acid
(D)
Cyanocobalamin
171. Laboratory
diagnosis of vitamin B12 deficiency can be made by measuring the
urinary excretion of
(A) Xanthurenic
acid
(B)
Formiminoglutamic acid
(C) Methylmalonic acid
(D)
Homogentisic acid
172. The
molecule of vitamin A1 contains
(A) Benzene
ring
(B) β-Ionone ring
(C) β-Carotene
ring
(D) None of
these
173. Precursor
of Vitamin A is
(A) α-Carotene
(B) β-Carotene
(C) γ-Carotene
(D) All of these
174. Two
molecules of vitamin A can be formed
from 1 molecule of
(A) α-Carotene
(B) β-Carotene
(C) γ-Carotene
(D) All of
these
175. Conversion
of β-carotene into retinal
requires the presence of
(A) β-Carotene
dioxygenase
(B) Bile salts
(C) Molecular
oxygen
(D) All of these
176. Conversion
of retinal into ritonal requires
the presence of
(A) NADH
(B) NADPH
(C) FADH2
(D) Lipoic acid
177. Retinal
is converted into retinoic acid in
the presence of
(A) Retinal
oxidase
(B) Retinal
carboxylase
(C) Retinene
reductase
(D) Spontaneously
178. Vitamin
A absorbed in intestine is
released into
(A) Portal
circulation
(B) Lacteals
(C) Both (A)
and (B)
(D) None of
these
179. Vitamin
A is stored in the body in
(A) Liver
(B) Adipose
tissue
(C)
Reticuloendothelial cells
(D) All of
these
180. Rhodopsin
contains opsin and
(A) 11-cis-retinal
(B) 11-trans-retinal
(C) All-cis-retinal
(D) All
trans-retinal
181. When
light falls on rod cells
(A)
All-cis-retinal is converted into all-trans-retinal
(B) 11-cis-retinal
is converted into 11-trans-retinal
(C) 11-trans-retinal
is converted into all-transretinal
(D) 11-cis-retinal is converted into
all-trans-retinal
182. Conversion
of all-trans-retinal into all-
trans-retinol requires
(A) NAD
(B) NADH
(C) NADP
(D) NADPH
183. Retinol
isomerase is present in
(A) Retina
(B) Liver
(C) Both (A)
and (B)
(D) None of
these
184. Anti-oxidant
activity is present in
(A) β-Carotene
(B) Retinol
(C) Retinoic
acid
(D) All of
these
185. One
international Unit of vitamin A is the activity present in
(A) 0.3 µg of β-Carotene
(B) 0.3 µg of
retinol
(C) 0.6 µg
of retinoic acid
(D) All of
these
186. Daily
requirement of vitamin A in an adult
man can be expressed as
(A) 400 IU
(B) 1,000
IU
(C) 5,000 IU
(D) 10,000
IU
187. Vitamin
B6 includes
(A) Pyridoxal
(B)
Pyridoxamine
(C) Pyridoxine
(D) All of these
188. An early
effect of vitamin a deficiency is
(A)
Xerophthalmia
(B) Keratomalacia
(C) Prolonged dark adaptation time
(D) Follicular
hyperkeratosis
189. Nyctalopia
is
(A) Drying of
eyes
(B) Destruction of cornea
(C) Blindness
(D) Inability to see in dimlight
190. Rod
cells possess a trans-membrane protein which is
(A) Adenylate
cyclase
(B) Transducin
(C) Rhodopsin
(D) B as well
as C
191. Provitamins
A include
(A) Retinal
(B) Retionic
acid
(C) Carotenes
(D) All of
these
192. Retinoic
acid can
(A) Act as a
photo receptor
(B) Support growth and differentiation
(C) Act as an
anti-oxidant
(D) None of
these
193. Prosthetic
group in cone cell phototreceptors is
(A) Iodine
(B) Opsin
(C) 11-cis-retinal
(D)
all-trans-retinal
194. Retinoic
acid is involved in the synthesis
of
(A) Rhodopsin
(B) Iodopsin
(C)
Porphyrinopsin
(D) Glycoproteins
195 Transducin
is a
(A) Signal
transducer
(B) Stimulatory
G-protein
(C) Trimer
(D) All of these
196. Provitamin
D3 is
(A)
Cholecalciferol
(B) Ergosterol
(C) 7-Dehydrocholesterol
(D) Ergocaliferol
197. Ergosterol
is found in
(A) Animals
(B) Plants
(C) Bacteria
(D) All of
these
198. A
provitamin D synthesized in human
beings is
(A) Ergosterol
(B) 7-Dehydrocholesterol
(C) Cholecalciferol
(D) 25-Hydroxycholecalciferol
199. 25-Hydroxylation
of vitamin D occurs in
(A) Skin
(B) Liver
(C) Kidneys
(D) Intestinal
mucosa
200. Tubular
reabsorption of calcium is
increased by
(A)
Cholecalciferol
(B) 25-Hydroxycholecalciferol
(C) Calcitriol
(D) All of
these
201. Parathormone
is required for the conversion of
(A)
Cholecalciferol into 1-hydroxycholecalciferol
(B) Cholecalciferol into
25-hydroxycholecalciferol
(C) 25-Hydroxycholecalciferol into calcitriol
(D) Cholesterol
into 7-dehydrocholesterol
202. Calcitriol
inhibits the conversion of
(A) Cholesterol
into 7-dehydrocholesterol
(B) Cholecalciferol into
1-hydroxycholecalciferol
(C)
Cholecalciferol into 25-hydroxycholecalciferol
(D) 25-Hydroxycholecalciferol into 1,25-
dihydroxycholecalciferol
203. Bowlegs
and knock-knees can occur in
(A) Rickets
(B)
Osteomalacia
(C) Both A and
B
(D)
Hypervitaminosis D
204. Calcification
of soft tissues can occur in
(A)
Osteomalacia
(B) Rickets
(C) Hypervitaminosis D
(D) None of
these
205. Levels
of serum calcium and inorganic
phosphorus are increased in
(A) Hypervitaminosis D
(B) Hypoparathyroidism
(C)
Hypovitaminosis D
(D) None of
these
206. Requirement
of vitamin E increases with
the increasing intake of
(A) Calories
(B) Proteins
(C) PUFA
(D) Cholesterol
207. In human
beings, vitamin E prevents
(A) Sterility
(B) Hepatic
necrosis
(C) Muscular
dystrophy
(D) None of these
208. Vitamin
E protects
(A) Polyunsaturated fatty
acids against aperoxidation
(B) Vitamin A
and carotenes against oxidation
(C) Lung tissue
against atmospheric pollutants
(D) All of these
209. Intestinal
bacteria can synthesise
(A)
Phyllogquinone
(B) Farnoquinone
(C) Both (A)
and (B)
(D) Menadione
210. A water
soluble form of vitamin K is
(A)
Phylloquinone
(B)
Farnoquinone
(C) Menadione
(D) None of
these
211. Prothrombin
time is prolonged in
(A) Vitamin K
deficiency
(B) Liver
damage
(C) Both (A) and (B)
(D) None of
these
212. A
synthetic form of vitamin K is
(A) Menadione
(B)
Farnoquinone
(C)
Phylloquinone
(D) None of
these
213. Retinal
is reduced to retinol by retinene reductase in presence of the coenzyme
(A) NAD+
(B) NADP+
(C) NADH + H+
(D) NADPH + H+
214. Retinal
exists as an ester with higher fatty acids in the
(A) Liver
(B) Kidney
(C) Lung
(D) All of these
215. Retinol
is transported to the blood as retinol attached to
(A) α1-globulin
(B) α2-globulin
(C) β-globulin
(D) γ-globulin
216. Carotenes are transported with the
(A) Minerals
(B) Proteins
(C) Lipids
(D) Lipoproteins
217. The
drugs that form complexes with
pyridoxal are
(A) Isoniazid
(B)
Penicillamine
(C) Rifampicin
(D) Both (A) and (B)
218. In the
blood the vitamin esters are attached to
(A) α1-lipoproteins
(B) α2-lipoproteins
(C) β-lipoproteins
(D)
γ-lipoproteins
219. The
percentage of Vitamin A in the form of esters is stored in the liver:
(A) 80
(B) 85
(C) 90
(D) 95
220. The
performed Vitamin A is supplied by
foods such as
(A) Butter
(B) Eggs
(C) Fish liver
oil
(D) All of these
221. The
non-protein part of rhodopsin is
(A) Retinal
(B) Retinol
(C) Carotene
(D) Repsin
222. Lumirhodopsin
is stable only at a temperature below
(A) -35°C
(B) -40°C
(C) -45°C
(D) -50°C
223 The
normal concentration of vitamin A in blood in I.V/dl:
(A) 20-55
(B) 24-60
(C) 30-65
(D) 35-70
224. Continued
intake of excessive amounts of vitamin A especially in children produces
(A)
Irritability
(B) Anorexia
(C) Headache
(D) All of these
225. Vitamin
D2 is also said to be
(A) Activated
ergosterol
(B)
Fergocalciferol
(C) Viosterol
(D) All of these
226. The poor
sources of vitamin D:
(A) Eggs
(B) Butter
(C) Milk
(D) Liver
227. The
activity of tocopherols is destroyed
by
(A) Oxidation
(B) Reduction
(C) Conjugation
(D) All of
these
228 Some
tocopherols are
(A) Terpenoid in structure
(B) Dional in
structure
(C) Isoprenoid in
structure
(D) Farnesyl in
structure
229. The
methyl groups in the aromatic nucleus
of a tocopherols are
(A) 2
(B) 3
(C) 4
(D) 5
230. Vitamin
E stored in
(A)
Mitochondria
(B) Microsomes
(C) Both (A) and (B)
(D) None of
these
231. Vitamin
E protects the polyunsaturated fatty acids from oxidation by molecular
oxygen in the formation of
(A) Superoxide
(B) Peroxide
(C) Trioxide
(D) All of
these
232. The
tocopherols prevent the oxidation of
(A) Vitamin A
(B) Vitamin D
(C) Vitamin K
(D) Vitamin C
233. Vitamin
E protects enzymes from destruction in
(A) Muscles
(B) Nerves
(C) Gonads
(D) All of these
234. Vitamin
K regulates the synthesis of blood clotting factors:
(A) VII
(B) IX
(C) X
(D) All of these
235. Ascorbic
acid can reduce
(A) 2,
4-dinitro benzene
(B) 2, 6-Dichlorophenol Indophenol
(C) 2,
4-dibromobenzene
(D) 2,
6-dibromo benzene
236. Sterilized
milk is devoid of
(A) Vitamin A
(B) Vitamin B1
(C) Vitamin C
(D) Vitamin D
237. The
symptoms of scurvy are
(A) Poor
healing of wounds
(B) Loosening of teeth
(C) Anaemia
(D) All of
these
238. Kwashiorkor
results from
(A) Vitamin A
deficiency
(B) Vitamin D
deficiency
(C) Deficiency
of minerals in diet
(D) Protein and caloric deficiency in diet
239. Which
among the following fatty acids is an essential fatty acid for man?
(A) Palmitic
acid
(B) Oleic acid
(C) Linoleic acid
(D) None of
these
240. The
number of nutritionally essential
amino acids for man is
(A) 6
(B) 8
(C) 10
(D) 12
241. Avidin
is present in
(A) Cow’s milk
(B) Raw egg
(C) Green leafy
vegetables
(D) Carrots
242. Marasmus
is due to malnutrition of
(A) Proteins
(B) Proteins and calories
(C) Proteins
and vitamins
(D) Proteins
and minerals
243. Energy
value in kilocalorie per gram of
fat in the body is
(A) 1
(B) 4
(C) 9
(D) 18
244. Which
among the following is an essential
amino acid for man?
(A) Alanine
(B) Serine
(C) Valine
(D) Glutamic
acid
245. Under
what condition to basal metabolic
rate goes up?
(A) Cold environment
(B) Hot
environment
(C) Intake of
base forming foods
(D)
Hypothyroidism
246. What is
the major form of caloric storage
in human body?
(A) ATP
(B) Glycogen
(C) Creatine phosphate
(D)
triacylglycerol
247. The phosphoprotein
of milk is
(A) Lactalbumin
(B)
Lactoglobulin
(C) Vitellin
(D) Caein
248. Dictary
deficiency of this vitamin leads to
night blindness:
(A) Retinol
(B) Niacin
(C) Ascorbic
acid
(D)
Cholecalciferol
249. A non
essential amino acid is not
(A) Absorbed in
the intestines
(B) Required in the diet
(C)
Incorporated into the protein
(D) Metabolized
by the body
250. The
deficiency of Vitamin B12 leads to
(A) Pernicious
anaemia
(B) Megablastic
anaemia
(C) Both (A) and (B)
(D) None of
these
251. Which
among the following is a nutritionally essential amino acid for man?
(A) Alanine
(B) Glycine
(C) Tyrosine
(D) Isoleucine
252. The
maximum specific dynamic action of
food stuff is exerted by
(A)
carbohydrates
(B) fats
(C) proteins
(D) vitamins
253. The
essential amino acids
(A) must be supplied
in the diet because the organism has lost the capacity to aminate the
corresponding ketoacids
(B) must be supplied in the diet because the
human has an impaired ability to synthesize
the carbon
chain of the corresponding ketoacids
(C) are
identical in all species studied
(D) are defined
as these amino acids which cannot be synthesized by the organism at a
rate adequate to meet metabolic requirements
254. Fibre in
the diet is beneficial in
(A) Hyper
glycemia
(B) Hyper cholseteremia
(C) Colon
cancer
(D) All of these
255 Sucrose
intolerance leads to
(A) Hyper
glycemia
(B) Glycosuria
(C) Diarrhoea
(D)
Hypoglycemia
256. There
can be intolerance with respect to
the following sugar:
(A) Glucose
(B) Lactose
(C) Maltose
(D) Xylose
257. Milk
contains very poor amounts of
(A) Calcium
(B) Phosphate
(C) Iron
(D) Riboflavin
258. Egg
contains very little
(A) Fat
(B) Proteins
(C) Carbohydrates
(D) Calcium
and phosphorus
259. BMR
(Basal Metabolic rate) is elevated in
(A) Hyper thyroidism
(B) Under
nutrition
(C) Starvation
(D)
Hypothyroidism
260. Soyabean
proteins are rich in
(A) Lysine
(B) Alanine
(C) Glcyine
(D) Aspartic
acid
261. Corn and
gliadin are low in
(A) Lysine
(B) Alanine
(C) Glycine
(D) Aspartic acid
262. What is
the disease caused by thiamine
deficiency?
(A) Nycalopia
(B) Scurvy
(C) Rickets
(D) Beriberi
263. Retinol
and retinol -binding protein (RBP)
bound with this protein:
(A) Albumin
(B) Prealbumin
(C) α2-globulin
(D) β-globulin
264. Megaloblastic
anemia is caused by the
deficiency of
(A) Folic acid
(B) Vitamin B6
(C) Iron
(D) Protein
265. This
vitamin acts as anti-oxidant:
(A) Vitamin
A
(B) Vitamin D
(C) Vitamin E
(D) Vitamin K
266. Calcitriol
is
(A) 1-OH-cholecalciferol
(B) 25-OH-cholecalciferol
(C) 24,
25-diOH cholecalciferol
(D) 1, 25-diOH cholecalciferol
267. 1-hydroxylation
of 25-OH vitamin D3
takes place in
(A) Liver
(B) Kidneys
(C) Intestine
(D) Pancreas
268. 25-hydroxylation
of vitamin D3 takes place in
(A) Liver
(B) Kidneys
(C) Intestine
(D) Pancreas
269. Hydroxylation
of 25-hydroxy chole-
calciferol is promoted by
(A) Cytochrome
- a
(B) Parathyroid hormone
(C)
Cytochrome-b
(D) CAMP
270. The egg
injury factor in raw egg white is
(A) Biotin
(B) Avidin
(C) Albumin
(D) Calcium
salts
271. The
following has cyanide:
(A) Vitamin B12
(B) Adenyl
cobamide
(C)
Benzimidazole cobamide
(D) Methyl
cobamide
272. The
human species can biosynthesize
(A) Vitamin C
(B) Vitamin B12
(C) Thiamine
(D) Niacin
273. Retina
contains this photosensitive
pigment:
(A) Rhodopsin
(B) Opsin
(C) Retinol
(D) Melanin
274. Anti
xerophthalmic vitamin is
(A) Vitamin B1
(B) Vitamin B2
(C) Vitamin B6
(D) Vitamin A
275. One of
the following is not a symptom of addison’s disease.
(A)
Hypoglycemia
(B)
Hyponatremia
(C) Hypokalemia
(D)
Hypochoremia
276. Gammaxane
is an antimetabolite of
(A) Thiamine
(B) Riboflavin
(C) Pyridoxin
(D) Inositol
277. Pyridoxin
deficiency may lead to convulsions as it is needed for the synthesis of
(A) GABA
(B) PABA
(C) EFA
(D) SAM
278. Sulpha
drugs are antimetabolities of
(A) Vitamin K
(B) Pyridoxin
(C) Folic acid
(D) Vitamin B2
279. This
abnormal metabolite may be responsible for the neurological manifestation
of pernicious anemia:
(A) Taurine
(B) Methyl
malonic acid
(C) Xantherunic
acid
(D) Phenyl
pyruvic acid
280. The
vitamin in leafy vegetables:
(A) D
(B) K
(C) A
(D) Both (B) and (C)
281. Isonicotinic
acid hydrazide given in the treatment of tuberculosis may lead to a
deficiency of
(A) Vitamin A
(B) Pyridoxin
(C) Folate
(D) Inositol
282. Biotin
is required for the reaction of CO2 with
(A) Water
(B) Acetyl CoA
(C) NH 3
(D)
Incorporation of carbon 6 in purine
283. A
deficiency of folate leads to
(A)
Megaloblastic anemia
(B) Aplastic anemia
(C) Pernicious
anemia
(D) Hypochromic
microcytic anemia
284. A
deficiency of Iron leads to
(A) Megaloblastic anemia
(B) Aplastic
anemia
(C) Pernicious
anemia
(D) Hypochromic
microcytic anemia
285. Corninoid
coenzymes are coenzymes of
(A) Vitamin B12
(B) Vitamin B6
C) Vitamin B2
(D) Vitamin B1
286. Vitamin
B12 initially binds to the proteins known as
(A)
Transcobalamin I
(B) R-Proteins
(C)
Transcobalamin II
(D) Intrinsic
factor of castle
287. Extrinsic
factor of castle is
(A) Vitamin B12
(B) Glycoprotein
(C) R-Proteins
(D) Sigma
protein
288. Intrinsic
factor of castle is
(A) Vitamin B12
(B)
Glycoprotein
(C) R-Proteins
(D) Sigma
protein
289. Pernicious
means
(A) Prolonged
(B) Dangerous
(C)
Intermittent
(D) Idiopathic
290. Reduction
of D-ribonucleotides to D-deoxy ribonucleotides in prokaryotes
requires
(A) 5, 6
dimethyl benzimidazole cobamide
(B) Thioredoxin
(C) Tetra
hydrobiopterin
(D) Tetra
hydrofolate
291. Biotin
is also known as
(A) Anti egg white injury factor
(B) Rutin
(C) Both (A)
and (B)
(D) None of
these
292. Angular
stomatosis is due to
(A)
Ariboflavinoses
(B) Deficiency of Vitamin C
(C) Deficiency
of Vitamin B1
(D) Deficiency
of folate
293. One of
the main functions of Vitamin K is
cofactor for
(A) Carboxylate
for the formation
of γ carboxyglutamate
(B) Methylation
of δ-adenosyl methionine
(C)
Carboxylation of biotin
(D) One carbon
transfer by tetrahydrofolate
294. Prothrombin
time is prolonged by administering
(A) Vitamin K
(B) Dicoumarol
(C) Calcium
(D) Prothrombin
295. This
vitamin acts as antioxidant.
(A) Vitamin A
(B) Vitamin D
(C) Vitamin E
(D) Vitamin K
296. This is
a photo-labile vitamin.
(A) Thiamine
(B) Riboflavin
(C) Niacin
(D)
Cholecalciferol
297. Convulsive
episodes occur when there is a severe deficiency of
(A) Pyridoxine
(B) Folic acid
(C) Thiamine
(D) Riboflavin
298. Metastatic
classification is seen in hyper-
vitaminosis:
(A) A
(B) K
(C) D
(D) E
299. The anti
vitamin for para aminobenzoic
acid is
(A) Aminopterin
(B) Dicoumarol
(C) Sulphonamides
(D) Thiopanic
acid
300. Several
pantothenic acid deficiency in man has been reported to cause
(A) Burning
feet syndrome
(B) Scurvy
(C) Cataract
(D)
Xerophthalmia
301. Cholesterol
is a precursor in the biogenesis of
(A) Vitamin A
(B) Vitamin D
(C) Vitamin E
(D) None of
these
302. This
vitamin is a potent antioxidant of vitamin A:
(A) Vitamin C
(B) Vitamin E
(C) Vitamin K
(D) Vitamin D
303. In
retinal rickets, the following hydroxylation of Vitamin D3 does not
take place:
(A) 25
(B) 1
(C) 24
(D) 7
304. The
following does not have phosphorous:
(A) Riboflavin
(B) TPP
(C) NAD+
(D) COASH
305. Convulsions
and delirium could be caused by a severe deficiency of
(A) Thiamine
(B) Glutamate
(C) Niacin
(D) Magnesium
306. Rice
polishings contain this vitamin:
(A) Riboflavin
(B) Niacin
(C) Thiamine
(D) Vitamin B12
307. In beri
beri there will be accumulation of_______ in blood.
(A) Aceto
acetic acid
(B) β-OH
butyric acid
(C) Pyruvic acid
(D) Methyl
malonic acid
308. Symptoms
of pellagra are
(A) Dermatitis
and diarrhea only
(B) Dermatitis
and dementia only
(C) Diarrhea, dermatitis and dementia
(D) Diarrhea
and elements only
309. Pyridoxine
deficiency leads to
(A)
Megaloblastic anemia
(B) Aplastic
anemia
(C) Hypochromic microcytic anemia
(D) Permicious
anemia
310. The
significant ocular lesion in arbo
flovinosis:
(A)
Keratomalacia
(B) Bitot’s spots
(C)
Vascularisation of the cornea
(D) lachrymal
metaplasia
311. Irradiation
of foods raises the content of
(A) Vitamin A
(B) Vitamin D
(C) Vitamin E
(D) Vitamin K
312. An
anti-vitamin for folic acid is
(A) Amethoptesin
(B) Dicoumarol
(C)
Pyrithoamine
(D) Isoniazid
313. Thymine
is
(A) Water
soluble vitamin
(B) Fat soluble
vitamin
(C) Purine base
(D) Pyrimidine base
314. The
anti-vitamin for para amino benzoic
acid is
(A)
Aminopterrin
(B) Dicoumarol
(C) INH
(D) Sulphonamides
315. The
sulphur-containing vitamins among
the following B-Vitamin is
(A) Thiamine
(B) Riboflavin
(C) Niacin
(D) Pyridoxine
316. Taurinuria
may be encountered in
(A) Permicious anemia
(B) Beriberi
(C) Pellegra
(D) Folate
deficiency
317. The
three vitamins which are specially required for proper nerve functions are
acid:
(A) Thiamine,
niacin and riboflavin
(B) Thiamine,
folic acid, choline
(C) Thiamine,
riboflavin, patothenic acid
(D) Thiamine, pyridoxin, vitamin B 12
318. This is
a rich source for vitamin C.
(A) Rice
(B) Milk
(C) Egg
(D) Lemon
319. The
following vitamin is involved in coenzyme function in transaminations:
(A)
Nicotinamide
(B) Pyridoxine
(C) Thiamine
(D) Riboflavin
320. Methyl
malonic aciduria is seen in the
deficiency of
(A) Vitamin B6
(B) Folic acid
(C) Thiamine
(D) Vitamin B 12
321. Deficiency
of Vitamin C leads to
(A) Rickets
(B) Scurvy
(C) Night blindness
(D) All of
these
322. If no
primer DNA was given, the following scientist could not have synthesized DNA.
(A) Ochoa
(B) Okazaki
(C) Kornberg
(D) Monod
323. Antisterility
vitamin is
(A) Vitamin B1
(B) Vitamin B2
(C) Vitamin E
(D) Vitamin K
324. All the
following vitamins give rise to cofactors that are phosphorylated in the
active form except
(A) Vitamin A
(B) Vitamin B1
(C) Vitamin D
(D) Vitamin E
325. Molecular
Iron, Fe, is
(A) Stored in the body in combination with
Ferritin
(B) Stored
primarily in the spleen 2+
(C) Excreted in
the urine as Fe
(D) absorbed in
the intestine by albumin
326. Humans
most easily tolerate a lack of which of the following nutrients?
(A) Protein
(B) Iodine
(C) Carbohydrate
(D) Lipid
327. A
deficiency of vitamin B12 causes
(A) Cheliosis
(B) Beriberi
(C) Pernicious anemia
(D) Scurvy
328. In
adults a severe deficiency of vitamin D causes
(A) Night
blindness
(B) Osteomalacia
(C) Rickets
(D) Skin cancer
329. Which of
the following vitamins would most likely become deficient in a person
who develops a completely carnivorous life style?
(A) Thiamine
(B) Niacin
(C) Cobalamine
(D) Vitamin C
330. Which of
the following statements regarding Vitamin A is true?
(A) It is not
an essential Vitamin
(B) It is
related to tocopherol
(C) It is a component of rhodopsin
(D) It is also
known as Opsin
331. Fully
activated pyruvate carboxylase depends upon the presence of
(A) Malate and
Niacin
(B) Acetyl CoA and biotin
(C) Acetyl CoA
and thiamine pyrophosphate
(D)
Oxaloacetate and biotin
332. Pantothenic
acid is a constituent of
coenzyme involved in
(A) Acetylation
(B)
Decarboxylation
(C)
Dehydrogenation
(D) Oxidation
333. Biotin
is involved in which of the following types of reactions?
(A)
Hydroxylation
(B) Carboxylation
(C)
Decarboxylation
(D) Deamination
334. Which of
the following vitamins is the precurssor of CoA?
(A) Riboflavin
(B) Pantothenate
(C) Thiamine
(D) Cobamide
335. Vitamins
that function as dinucleotide derivatives include all the following
except
(A) Thiamine
(B) Niacin
(C) Nicotinate
(D) Vitamin B2
336. Methyl
malonic aciduria is seen in a deficiency of
(A) Vitamin B6
(B) Folic acid
(C) Thiamine
(D) Vitamin B12
337. What is
the disease caused by thiamine deficiency?
(A) Nyctalopia
(B) Scurvy
(C) Rickets
(D) Beriberi
338. Retinol
and Retinol binding protein are bound with this protein:
(A) Albumin
(B) Prealbumin
(C) α-globulin
(D) β-globulin
339. Megaloblastic
anemia is caused by the
deficiency of
(A) Folic acid
(B) Vitamin B6
(C) Iron
(D) Protein
340. This
vitamin acts as anti oxidant.
(A) Vitamin A
(B) Vitamin D
(C) Vitamin E
(D) Vitamin K
341. Calcitriol
is
(A) 1-hydroxy cholecalciferol
(B) 25-hydroxy cholecalciferol
(C) 24,
25-dihydroxy cholecalciferol
(D) 1, 25-dihydroxy cholecalciferol
342. 1-hydroxylation
of 25-hydroxy Vitamin
D3 takes place in
(A) Liver
(B) Kidneys
(C) Intestine
(D) Pancreas
343. 25-hydroxylation
of Vitamin D3 takes
place in
(A) Liver
(B) Kidneys
(C) Intestines
(D) Pancreas
344. Hydroxylation
of 25-hydroxy cholecalciferol is promoted by
(A) Cytochrome
A
(B) Panthyroid hormone
(C) Cytochrome
b
(D) cAMP
345. The egg
injury factor in raw egg white is
(A) Biotin
(B) Avidin
(C) Albumin
(D) Calcium
salts
346. The
following has cyanide:
(A) Vitamin B12
(B) Adenyl
cobamide
(C)
Benzimidazole cobamide
(D) Methyl
cobamide
347. The
human species can biosynthesize
(A) Vitamin C
(B) Vitamin B12
(C) Thiamine
(D) Niacin
348. Retina
contains this photo sensitive pigment.
(A) Rhodopsin
(B) Opsin
(C) Retinol
(D) Malanin
349. Antixerophthalmic
vitamin is
(A) Vitamin B1
(B) Vitamin B2
(C) Vitamin B6
(D) Vitamin A
350. One of
the following is not symptom of Addison’s disease:
(A)
Hypoglycemia
(B) Hyponatremia
(C) Hypokalemia
(D)
Hypochloremia
351. Gammaxine
is an antimetabolite of
(A) Thiamine
(B) Riboflavin
(C) Pyridoxin
(D) Inositol
352. Pyridoxine
deficiency may lead to convulsions as it is needed for the synthesis
of
(A) GABA
(B) PABA
(C) EFA
(D) SAM
353. Sulpha
drugs are antimetabolites of
(A) PABA
(B) Pyridoxin
(C) Vitamin B2
(D) Pantothenic
acid
354. This
abnormal metabolite may be responsible for the neurological manifestation
of pernicious anemia.
(A) Taurine
(B) Methyl malonic acid
(C) Xanthurenic
acid
(D) Phenyl
pyruvic acid
355. Choline
is not required for the formation of
(A) Lecithins
(B) Acetyl
choline
(C)
Sphingomyelin
(D) Cholic acid
356. Isonicotinic
acid hydrazide given in the treatment of tuberculosis may lead to a
deficiency of
(A) Vitamin A
(B) Pyridoxin
(C) Folate
(D) Inositol
357. Steroidal
prohormone is
(A) Vitamin
A
(B) Vitamin C
(C) Vitamin D
(D) None of
these
358. A
deficiency of folate leads to
(A) Megaloblastic anemia
(B) Aplastic anemia
(C) Pernicious
anemia
(D) Hypochromic
microcytic anemia
359. Deficiency
of Iron leads to
(A) Megaloblastic anemia
(B) Aplastic anemia
(C) Pernicious
anemia
(D) Hypochromic microcytic anemia
360. Corrinoid
coenzymes are coenzymes of
(A) Vitamin
B6
(B) Vitamin B12
(C) Vitamin
B2
(D) Vitamin B1
361. Vitamin
B12 initially binds to the proteins known as
(A)
Transcobalamin I
(B) R-proteins
(C) Transcobalamin
II
(D) Intrinsic
factor of castle
362. Extrinsic
factor of castle is
(A) Vitamin B12
(B)
Glycoprotein
(C) R-proteins
(D) Sigma
protein
363. Intrinsic
factor of castle is
(A) Vitamin
B12
(B) Glycoprotein
(C) R-proteins
(D) Sigma
protein
364. Pernicious
means
(A) Prolonged
(B) Dangerous
(C) Intermittent
(D) Idiopathic
365. Reduction
of D-ribonucleotides to D-deoxyribonucleotides in prokaryotes requires
(A) 5, 6
dimethyl benzimindazole cobamide
(B) Thiredoxin
(C) Tetra
hydrobiopterin
(D) Tetra
hydrofolate
366. Antirachitic
vitamin is
(A) Vitamin A
(B) Vitamin D
(C) Vitamin E
(D) Vitamin K
367. Angular
stomatitis is due to
(A) Ariboflavinosis
(B) Deficiency
of Vitamin C
(C) Deficiency
of Vitamin B1
(D) Deficiency
of folate
368. One of
the main functions of Vitamin K is the cofactor for
(A) Carboxylase for the formation of γ--carboxy glutamate
(B) Methylation
by S-adenosyl methionine
(C)
Carboxylation by biotin
(D) One carbon
transfer by tetra hydrofolate
369. Prothrombin
time is prolonged by administering
(A) Vitamin K
(B) Dicoumarol
(C) Calcium
(D) Prothrombin
370. This
Vitamin acts as antioxidant:
(A) Vitamin A
(B) Vitamin D
(C) Vitamin E
(D) Vitamin K
371. This is
photo labile vitamin:
(A) Thiamine
(B) Riboflavin
(C) Niacin
(D)
Cholecalciferol
372. Convulsive
episodes occur when there is a severe deficiency of:
(A) Pyridoxine
(B) Folic acid
(C) Thiamine
(D) Riboflavin
373. Metastatic
calcification is seen in hypervitaminosis:
(A) A
(B) K
(C) D
(D) E
374. The
anti-vitamin for para amino benzoic acid is
(A) Aminopterin
(B) Dicoumasol
(C) Sulphanomides
(D) Thiopamic
acid
375. Severe
patothemic acid deficiency in man has been reported to cause
(A) Burning feet syndrome
(B) Scurvy
(C) Cataract
(D)
Xeropththalmia
376. Cholesterol
is a precursor in the biogenesis
of
(A) Vitamin A
(B) Vitamin D
(C) Vitamin E
(D) None of
these
377. Which of
the vitamins is a potent anti-oxidant of Vitamin A?
(A) Vitamin C
(B) Vitamin E
(C) Vitamin K
(D) Vitamin D
378. In renal
rickets, the following hydroxylation of Vitamin D3 does not take
place:
(A) 25
(B) 1
(C) 24
(D) 7
379. Which of
the following does not have phosphorous?
(A) Riboflavin
(B) TPP
(C) NAD+
(D) CaASH
380. Rice-polishings
contain whcih of the following Vitamin?
(A) Riboflavin
(B) Niacin
(C) Thiamine
(D) Vitamin B12
381. In beri
beri there will be accumulation of_________ in blood.
(A) Aceto
acetic acid
(B) β−hydroxy
butyric acid
(C) Pyruvic acid
(D) Methyl
malonic acid
382. Symptoms
of pellagra are
(A) Dermatitis
and diarrhea only
(B) Dermatitis and Dermentia only
(C) Diarrhea
and dermentia only
(D) Diarrhea, Dermatitis and dementia
383. Pyridoxine
deficiency leads to
(A)
Megaloblastic anemia
(B) Aplastic
anemia
(C) Hypochromic microcytic anemia
(D) Pernicious
anemia
384. The
significant ocular lesion in a ribofla-
vinosis is
(A)
Keratomalacia
(B) Bitot’s
spots
(C) Vascularisation of the cornea
(D) Lachrynal
metaplasia
385. An
anti-vitamin for folic acid is
(A) Aminopterin
(B) Dicoumarol
(C)
Pyrithiamine
(D) Isoniazid
386. Thiamine
is
(A)
Water-soluble vitamin
(B) Fat soluble
vitamin
(C) Purine base
(D) Pyrimidine base
387. The
anti-vitamin for para amino benzoic
acid is
(A) Aminopterin
(B) Dicoumarol
(C) INH
(D) Sulphanomides
388. The
sulphur containing vitamins among the following B Vitamin is
(A) Thiamine
(B) Riboflavin
(C) Niacin
(D) Pyridoxine
389. Taurinuria
may be encountered in
(A) Pernicious anemia
(B) Beriberi
(C) Pellegra
(D) Folate
deficiency
390. The
three vitamins which are specially required for proper nerve functions are
(A) Thiamine,
Niacin and Riboflavin
(B) Thiamin,
Folic acid, Choline
(C) Thiamine,
Riboflavin, Pantothenic acid
(D) Thiamine, Pyridoxin, Vitamin B12
391. This is a rich source for Vitamin C:
(A) Rice
(B) Milk
(C) Egg
(D) Lemon
392. Which ot
the following vitamin is involved in coenzyme function in transaminations?
(A)
Nicotinamide
(B) Pyridoxine
(C) Thiamine
(D) Riboflavin
393. Methyl
malonic aciduria is seen in a
deficiency of
(A) Vitamin B6
(B) Folic acid
(C) Thiamine
(D) Vitamin B12
394. In
pernicious anemia, Urine contains high
amounts of
(A) Methyl malonic acid
(B) FIGLU
(C) VMA
(D) 5 HIAA
395. Anti
sterility Vitamin is
(A) Vitamin B1
(B) Vitamin B2
(C) Vitamin E
(D) Vitamin K
396. Biotin
deficiency is characterized by the
following except
(A) Muscular
pain
(B) Anaemia
(C) Nausea
(D) Dermatitis
397. Deficiency
of thiamine causes
(A) Beri beri
(B) Scurvy
(C) Night
blindness
(D) Rickets
398. Deficiency
of Vitamin D leads to
(A) Rickets
(B)
Osteomalacia
(C)
Xeropthalmia
(D) Both (A)
and (B)
399. The
vitamin that is useful in cancer is
(A) A
(B) B complex
(C) C
(D) E
400. Vitamin
A over dosage causes injury to
(A)
Mitochondria
(B)
Microtubules
(C) Lysosomes
(D) E.R
401. Which is
a pro vitamin or vitamin that has antioxidant properties?
(A) Beta
carotene
(B) Vitamin E
(C) Vitamin C
(D) Vitamin D
402. The
vitamin required for carboxylation
reaction is
(A) Vitamin B2
(B) Vitamin B6
(C) Biotin
(D) Vitamin B12
403. Biological
activity of tocopherols has been attributed in part to their action as
(A) Antioxidant
(B) Anticoagulents
(C) Provitamin
(D) Carriers in
electron transport system
404. Biotin
is essential for
(A) Translation
(B) Carboxylation
(C)
Hydroxylation
(D)
Transamination
405. Which of
the following vitamin act as a respiratory catalyst?
(A) B2
(B) Pyridoxine
(C) B12
(D) C
406. Metal in
Vitamin B12 is
(A) Copper
(B) Cobalt
(C) Iron
(D) Zinc
407. Whole
wheat is an excellent source of
(A) Vitamin D
(B) Vitamin C
(C) Vitamin A
(D) Thiamine
408. Vitamin
used in the treatment of homo-
cystinuria is
(A) B1
(B) B5
(C) B12
(D) B6
409. Which of
the following is not a component
of coenzyme A?
(A) Pantothenic
acid
(B) Adenylic
acid
(C) Acetic acid
(D) Sulfhydryl
group
410. The most
active form of Vitamin D is
(A) 25-Hydroxycholecalciferol
(B) 1,
25-dihydroxycholecalciferol
(C) 25-dihydroxyergocalciferol
(D) None of
these
411. The
important part in the structure of
flavoprotein is
(A) Vitamin B6
(B) Vitamin B2
(C) Vitamin B1
(D) Vitamin A
412. Vitamin
essential for transamination is
(A) B1
(B) B2
(C) B6
(D) B12
413. The
action of Vitamin K in formation of clotting factor is through
(A) Post
transcription
(B) Post translation
(C) Golgi complex
(D) Endoplasmic
reticulum
414. Vitamin
necessary for CoA synthesis:
(A) Pantothenic acid
(B) Vitamin C
(C) B6
(D) B12
415. Cofactor
for transamination is
(A) Thymine
(B) Riboflavin
(C) Pyridoxine
(D) Niacin
416. During
deficiency of thiamine the concentration of the following compound rises
in blood and intracellular fluid:
(A) Glycogen
(B) Sugar
(C) Amino acids
(D) Pyruvic acid
417. The
conversion of carotenoids to Vitamin
A takes place in
(A) Intestine
(B) Liver
(C) Kidney
(D) Skin
418. Man
cannot synthesize vitamin:
(A) A
(B) B
(C) C
(D) D
419. Vitamin
A is required for the formation of a light receptor protein known as
(A) Globulin
(B) Lypoprotein
(C)
Chomoprotein
(D) Rhodospin
420. Excessive
vitamin A in children produces
(A)
Irritability
(B) Anorexia
(C) Headache
(D) All of these
421. Tocopherols
prevent the oxidation of
(A) Vitamin A
(B) Vitamin D
(C) Vitamin K
(D) Vitamin C
422. Vitamin
K regulates the synthesis of blood clotting factors.
(A) VII
(B) IX
(C) X
(D) All of these
423. The
colour of cyanomethmoglobin is
(A) Pale yellow
(B) Pink
(C) Brown
(D) Bright red
424. Transketolase
activity is affected in
(A) Bitoin
deficiency
(B) Pyridoxine deficiency
(C) PABA
deficiency
(D) Thiamine deficiency
425. The
hydrolysis of glucose-6-PO4 is catalyzed by a phosphatase that is
not found
in which of the following?
(A) Liver
(B) Kidney
(C) Muscle
(D) Small
intestine
426. Vitamin K2
was originally isolated from
(A) Soyabean
(B) Putrid fishmeal
(C) Alfa alfa
(D) Oysters
427. The following
form of vitamin A is used in the visual cycle:
(A) Retinol
(B) Retinoic
acid
(C) Retinaldehyde
(D) Retinyl
acetate
428. Increased
carbohydrate consumption increases the dietary requirement for
(A) Thiamine
(B) Riboflavine
(C) Pyridoxine
(D) Folic acid
429. Increased
protein intake is accompanied by an increased dietary requirement for
(A) Thiamine
(B) Riboflavine
(C) Folic acid
(D) Nicotininic
acid
430. The deficiency
of which one of the following vitamin causes creatinuria?
(A) Vitamin E
(B) Vitamin K
(C) Vitamin A
(D) Vitamin B6
431. A
biochemical indication of vitamin B12 deficiency can be obtained by
measuring
the urinary excretion of
(A) Pyruvic
acid
(B) Malic acid
(C) Methyl malonic acid
(D) Urocanic
acid
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